| 产品描述: | 产品介绍Columbianadin (Zosimin, 2-Butenoic acid) 是一种来自当归的天然香豆素,已知具有多种生物活性,包括钙通道阻断活性、对各种癌细胞系的细胞毒活性、镇痛活性、肠道吸收和运输、抗炎和抗癌作用。;Product introductionColumbianadin, a natural coumarin from, is known to have various biological activities including anti-inflammatory and anti-cancer effects. |
| 靶点: |
Apoptosis |
| 体内研究: |
The analysis method is successfully applied to a tissue distribution study of Columbianadin (CBN) and Columbianetin (CBT) after intravenous administration of Columbianadin to rats. The results of this study indicated that Columbianadin can be detected in all of the selected tissues after i.v. administration. Columbianadin is distributed to rat tissues rapidly and can be metabolized to CBT in most detected tissues. Of the detected tissues, heart had the highest uptake of Columbianadin, which suggests that heart might be one of the main target tissues of Columbianadin . |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.045 ml |
15.227 ml |
30.454 ml |
| 5 mM |
0.609 ml |
3.045 ml |
6.091 ml |
| 10 mM |
0.305 ml |
1.523 ml |
3.045 ml |
| 50 mM |
0.061 ml |
0.305 ml |
0.609 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |