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丁苯那嗪

    
10mM in DMSO

Tetrabenazine

源叶(MedMol)
T94159 一键复制产品信息
58-46-8
C19H27NO3
317.42
3-异丁基-9,10-二甲氧基-1,3,4,6,7,11b-六氢-2H-苯并[a]喹啉-2-酮;3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizin-2-one
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T94159-1ml促销
10mM in DMSO

¥720.00 ¥570.00

9 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: 强大的可逆VMAT2抑制剂;Potent, reversible VMAT2 inhibitor;Usually used for dopamine uptake assays in mouse brain cells,and also has been used for non-specific binding assays in postnuclear supernatants derived from PC-12 and CV-1 cells.;Usually used for dopamine uptake assays in mouse brain cells,and also has been used for non-specific binding assays in postnuclear supernatants derived from PC-12 and CV-1 cells.
参考文献: 1. J C Shih, et al. Ketanserin and tetrabenazine abolish aggression in mice lacking monoamine oxidase A. Brain Res. 1999 Jul 24;835(2):104-12.
2. Nobue Kitanaka, et al. Tetrabenazine, a vesicular monoamine transporter-2 inhibitor, attenuates morphine-induced hyperlocomotion in mice through alteration of dopamine and 5-hydroxytryptamine turnover in the cerebral cortex. Pharmacol Biochem Behav. 2018 Sep;172:9-16. doi: 10.1016/j.pbb.2018.07.002. Epub 2018 Jul 12.
3. S J Podurgiel, et al. The vesicular monoamine transporter (VMAT-2) inhibitor tetrabenazine induces tremulous jaw movements in rodents: implications for pharmacological models of parkinsonian tremor. Neuroscience. 2013 Oct 10;250:507-19. doi: 10.1016/j.neuroscience.2013.07.008. Epub 2013 Jul 15.
4. Kenney, C., C. Hunter, and J. Jankovic, Long-term tolerability of tetrabenazine in the treatment of hyperkinetic movement disorders. Mov Disord, 2007. 22(2): p. 193-7.
5. Jankovic, J. and J. Beach, Long-term effects of tetrabenazine in hyperkinetic movement disorders. Neurology, 1997. 48(2): p. 358-62.
6. Ondo, W.G., P.A. Hanna, and J. Jankovic, Tetrabenazine treatment for tardive dyskinesia: assessment by randomized videotape protocol. Am J Psychiatry, 1999. 156(8): p. 1279-81.
保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.15 ml 15.752 ml 31.504 ml
5 mM 0.63 ml 3.15 ml 6.301 ml
10 mM 0.315 ml 1.575 ml 3.15 ml
50 mM 0.063 ml 0.315 ml 0.63 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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