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SNX-2112 (PF-04928473)

    
10mM in DMSO

SNX-2112 (PF-04928473)

源叶(MedMol)
T94571 一键复制产品信息
908112-43-6
C23H27F3N4O3
464.48
4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T94571-1ml促销
10mM in DMSO

¥1850.00 ¥1470.00

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产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
参考文献: 1. Chandarlapaty S, et al. SNX2112, a synthetic heat shock protein 90 inhibitor, has potent antitumor activity against HER kinase-dependent cancers. Clin Cancer Res. 2008 Jan 1;14(1):240-8.
2. Mishra SJ, et al. Transformation of the Non-Selective Aminocyclohexanol-Based Hsp90 Inhibitor into a Grp94-Seletive Scaffold. ACS Chem Biol. 2017 Jan 20;12(1):244-253.
3. Huang KH, et al. Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents. J Med Chem. 2009 Jul 23;52(14):4288-305
4. Okawa Y, et al. SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK. Blood. 2009 Jan 22;113(4):846-55.
保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.153 ml 10.765 ml 21.529 ml
5 mM 0.431 ml 2.153 ml 4.306 ml
10 mM 0.215 ml 1.076 ml 2.153 ml
50 mM 0.043 ml 0.215 ml 0.431 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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