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NiCur

    
10mM in DMSO

NiCur

源叶(MedMol)
T94759 一键复制产品信息
2674753-39-8
C22H16N2O
324.38
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
T94759-1ml促销
10mM in DMSO

¥2200.00 ¥1980.00

货期:3-5天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述:

NiCur is a potent and selective CBP histone acetyltransferase (HAT) inhibitor with an IC 50 value of 0.35 μΜ. NiCur, which blocks CBP HAT activity and downregulates p53 activation upon genotoxic stress. NiCur can be used for performing mechanistic studiesIC50& Target:CBP-HAT 0.35 μM (IC 50 )In Vitro:NiCur (0.5~1 μM; U2OS cells) reduces the Dox-induced p53K382ac, p53S15p, and p53 levels in a dose-dependent manner. NiCur (1.5 μM) reduces the level of H3K27ac. NiCur (1.5 μM; U2OS cells) restores cellular proliferation. NiCur (Intestinal epithelialBiological Activity:NiCur is a potent and selective CBP histone acetyltransferase (HAT) inhibitor with an IC 50 value of 0.35 μΜ. NiCur, which blocks CBP HAT activity and downregulates p53 activation upon genotoxic stress. NiCur can be used for performing mechanistic studies

保存条件: -80℃(运输条件:冰袋低温运输)
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.083 ml 15.414 ml 30.828 ml
5 mM 0.617 ml 3.083 ml 6.166 ml
10 mM 0.308 ml 1.541 ml 3.083 ml
50 mM 0.062 ml 0.308 ml 0.617 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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