UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. UNC7467 reduces levels of inositol pyrophosphates. UNC7467 can be used for obesity research.IC50& Target:IC 50 : 4.9 nM (IP6K2), 8.9 nM (IP6K1), 1320 nM (IP6K3) .In Vitro:UNC7467 (2.5 μM; 3 hours; HCT116 cells) reduces levels of inositol pyrophosphates. UNC7467 reduces 5-InsP 7 levels by 81% and 5-InsP 8 levels by 63%. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In Vivo:UNC7467 (5mg/kg; i.p.; daily, for 4 weeks; diet-induced obesity mice) ameliorated diet induced obesity, insulin resistance, and hepatic steatosis. UNC7467 (1-5mg/kg; i.v. and i.p.; diet-induced obesity mice) exhibits low clearance (13.7 (mL/min)/kgBiological Activity:UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. UNC7467 reduces levels of inositol pyrophosphates. UNC7467 can be used for obesity research.