LRRK2 抑制剂;LRRK2 Inhibitors;;InformationCZC-54252 CZC-54252 is a potent and selective LRRK2 inhibitor with IC50s of 1.28 nM and 1.85 nM for human wild type LRRK2 and G2019S LRRK2, respectively.TargetsLRRK2 (WT) (Cell-free assay); LRRK2 (G2019S) (Cell-free assay) 1.28 nM; 1.85 nM
靶点:
IC50: 1.28 nM (Wild-type LRRK2) and 1.85 nM (G2019S LRRK2)