| 产品描述： | 由A40926制备的半合成糖肽;a semi-synthetic glycopeptide prepared from A40926;Dalbavancin 是一种半合成糖肽，由A40926通过在天然糖肽先前未开发的区域中引入带正电的亲脂性部分而制得。这种修饰提供了更长的体外半衰期，并提高了其对多种革兰氏阳性和多药耐药菌株（例如MRSA和MRSE）的体外活性。;Dalbavancin is a semi-synthetic glycopeptide prepared from A40926 by introducing a positively charged lipophilic moiety in a previously unexplored region of the natural glycopeptide. This modification provides a longer in vitro half life, and improved in vitro activity against a variety of Gram positive and multi-drug resistant isolates such as MRSA and MRSE. |
| 体内研究： |
Dalbavancin (15-240 mg/kg; intraperitoneal injection; every 36 h or 72 h; for 14 days; female BALB/c mice) treatment has a survival rate of 80% to 100% of mice with all dose regimens. |
| 保存条件： |
-80℃（运输条件：冰袋低温运输） |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
0.55 ml |
2.752 ml |
5.505 ml |
| 5 mM |
0.11 ml |
0.55 ml |
1.101 ml |
| 10 mM |
0.055 ml |
0.275 ml |
0.55 ml |
| 50 mM |
0.011 ml |
0.055 ml |
0.11 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京