| 产品描述: | 组蛋白去甲基化酶抑制剂;Histone Demethylase Inhibitors;;InformationZ-JIB-04 (NSC 693627) Z-JIB-04 (NSC 693627, JIB-04 Z-isomer) is an isomer of JIB-04. JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230 nM, 340 nM, 855 nM, 445 nM, 435 nM, 1100 nM and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.TargetsJARID1A (Cell-free assay); JMJD2D (Cell-free assay); JMJD2E (Cell-free assay); JMJD2B (Cell-free assay); JMJD2A (Cell-free assay) 32456,230 nM; 290 nM; 340 nM; 435 nM; 445 nM |