| 产品描述: | Akt 调节剂;Akt Modulators;产品介绍:Rotundic acid 是一种从圆形肠球菌 (I. rotunda) 中获得的三萜类化合物,可通过 AKT/mTOR 和 MAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。Rotundic acid 具有抗炎和保护心脏的能力。;InformationRotundic acid Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.RA induces cell cycle arrest, DNA damage, and apoptosis by modulating the AKT/mTOR and MAPK pathways . |