PORCN抑制剂;PORCN Inhibitors;;InformationIWP-O1 IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.Targetsporcn (Cell-based assay) 80 pM(EC50)In vitroIWP-O1 has significantly improved metabolic stability.Cell Research(from reference)Cell lines:HeLa cells Concentrations:1 μM Incubation Time:24 h