| 产品描述: | Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities. Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.;Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities. Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| 体内研究: |
Indoprofen (2 mg/kg, po, once daily for 2-12 weeks) 可提高小鼠的肌肉质量和力量,改善老年小鼠的肌肉功能。Indoprofen 可抑制肌管形成减少,增强小鼠对 Dexamethasone 引起的失用性肌肉萎缩的抗疲劳能力。 Indoprofen (20-40 mg/kg, ip, single dose) 可减轻脓毒症引起的炎症反应和组织损伤,提高脓毒症小鼠的存活率。 |
| 参考文献: |
1. Kim H, Cho SC, Jeong HJ, et al. Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway. J Cachexia Sarcopenia Muscle. 2020;11(4):1070-1088. 2. Bi X, et al., Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses. Toxicol Appl Pharmacol. 2021 Dec 15;433:115778. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.555 ml |
17.774 ml |
35.548 ml |
| 5 mM |
0.711 ml |
3.555 ml |
7.11 ml |
| 10 mM |
0.355 ml |
1.777 ml |
3.555 ml |
| 50 mM |
0.071 ml |
0.355 ml |
0.711 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |