产品应用:草酰乙酸是三羧酸循环的一个中间体,对新陈代谢至关重要。它是糖异生途径的一部分。丙酮酸羧化酶的突变会导致草酰乙酸的产生减少。它可抑制琥珀酸脱氢酶,是线粒体代谢的一种关键调节剂。草酰乙酸已被用作测定胞质杂合体和神经母细胞瘤细胞中柠檬酸合酶活性的底物。它也已被用于测定苹果酸脱氢酶的活化。 ;Oxaloacetic Acid substrate for malate dehydrogenase and oxaloacetate decarboxylase. Oxaloacetic Acid is an inhibitor of SDH.Oxaloacetic acid is a dicarboxylic acid. It is an intermediate in the citric acid cycle. It is highly soluble in water and is present ubiquitously. It is produced in the mitochondria by the action of pyruvate carboxylase on pyruvate. Breakdown products of oxaloacetate includes malate, pyruvate and aspartic acid.A malate dehydrogenase and oxaloacetate decarboxylase substrate