Src抑制剂;Src Inhibitors;;InformationKX1-004 KX1-004 is a non-ATP competitive inhibitor of Src protein tyrosine kinase (Src-PTK; IC50 = 40 µM).TargetsSrc-PTK 40 μM
体内研究:
KX1-004 (30 µM) provides significant protection against noise-induced temporary threshold shift (TTS), permanent threshold shift (PTS) and outer hair cells (OHC) loss. KX1-004 (50 mg/kg) is effective against noise exposure.