| 体内研究: |
Facinicline (RG3487) improves object recognition memory in rats after acute [minimally effective dose (MED) 1.0 mg/kg p.o.] or repeated (10 day) administration at brain and plasma concentrations in the low-nanomolar range. RG3487 (0.1–10 mg/kg p.o.) selectively enhances object recognition memory. |
| 参考文献: |
1. Tanya L Wallace, et al. RG3487, a Novel Nicotinic α7 Receptor Partial Agonist, Improves Cognition and Sensorimotor Gating in Rodents. J Pharmacol Exp Ther. 2011 Jan;336(1):242-53. |
| 保存条件: |
-80℃,干燥(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.26 ml |
16.298 ml |
32.596 ml |
| 5 mM |
0.652 ml |
3.26 ml |
6.519 ml |
| 10 mM |
0.326 ml |
1.63 ml |
3.26 ml |
| 50 mM |
0.065 ml |
0.326 ml |
0.652 ml |
|
| 注意: |
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