corrosion inhibitor; Inhibitor of inv(16) leukemia; bind to wild-type CBFb and inhibit CBFb binding to RUNX proteins; methionine aminopeptidase inhibitor;
靶点:
IC50: 2.086 µM (ecMetAP)
参考文献:
1. Schiffmann R, et al. Metal-mediated inhibition of Escherichia coli methionine aminopeptidase: structure-activity relationships and development of a novel scoring function for metal-ligand interactions. J Med Chem. 2006 Jan 26;49(2):511-22.