Bcr-Abl酪氨酸激酶活性的选择性变构抑制剂;Selective allosteric inhibitor of Bcr-Abl tyrosine kinase activity;GNF-2是一种高选择性,非ATP竞争性的Bcr-Abl抑制剂,对Flt3-ITD, Tel-PDGFR, TPR-MET和Tel-JAK1转化的肿瘤细胞没有作用活性。;GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl, shows no activity to Flt3-ITD, Tel-PDGFR, TPR-MET and Tel-JAK1 transformed tumor cells.An inhibitor of c-Abl and Bcr-abl activity