| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
V37789-1mg |
≥99% | ￥770.00 |
货期：3-5天 | - | - | - | - |
|
V37789-5mg |
≥99% | ￥1810.00 |
货期：3-5天 | - | - | - | - |
|
V37789-10mg |
≥99% | ￥2870.00 |
货期：3-5天 | - | - | - | - |
|
V37789-25mg |
≥99% | ￥4900.00 |
货期：3-5天 | - | - | - | - |
|
V37789-50mg |
≥99% | ￥6830.00 |
货期：3-5天 | - | - | - | - |
|
V37789-100mg |
≥99% | ￥9190.00 |
货期：3-5天 | - | - | - | - |
|
V37789-200mg |
≥99% | ￥12300.00 |
货期：3-5天 | - | - | - | - |
|
| 体内研究： | Clazosentan (10 μM, 0.05 mL/kg, intracisternal injection) inhibits the contractile responses to ET-1 in rats. Clazosentan (10 mg/kg, s.c.) inhibits IL-33-induced hypernociception in mice. |
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| 参考文献： | 1. Juif PE, et al. Clinical Pharmacology of Clazosentan, a Selective Endothelin A Receptor Antagonist for the Prevention and Treatment of aSAH-Related Cerebral Vasospasm. Front Pharmacol. 2021 Feb 4;11:628956. 2. Povlsen GK, et al. MEK1/2 inhibitor U0126 but not endothelin receptor antagonist clazosentan reduces upregulation of cerebrovascular contractile receptors and delayed cerebral ischemia, and improves outcome after subarachnoid hemorrhage in rats. J Cereb Blood Flow Metab. 2015 Feb;35(2):329-37. 3. Vatter H, et al. Cerebrovascular characterization of clazosentan, the first nonpeptide endothelin receptor antagonist clinically effective for the treatment of cerebral vasospasm. Part I: inhibitory effect on endothelin(A) receptor-mediated contraction. J Neurosurg. 2005 Jun;102(6):1101-7. 4. Verri WA Jr, Guerrero AT, Fukada SY, Valerio DA, Cunha TM, Xu D, Ferreira SH, Liew FY, Cunha FQ. IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2723-8. 5. Juif PE, et al. Influence of Rifampin-Mediated Organic Anion-Transporting Polypeptide 1B1/1B3 Inhibition on the Pharmacokinetics of Clazosentan. Clin Transl Sci. 2019 Sep;12(5):440-444. |
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| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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