| 产品描述: | Manool 是Salvia officinalis中的二萜。Manool 在癌细胞中诱导选择性的细胞毒性。Manool 使癌细胞停滞在细胞周期的 G(2)/M 期。 |
| 体外研究: |
Manool exhibits higher cytotoxic activity against HeLa (IC50=6.7 µg/mL) and U343 (IC50=6.7 µg/mL) cells. Manool exhibits a protective effect against chromosome damage induced by MMS in HepG2 cells. |
| 参考文献: |
1. de Oliveira PF, et al. Manool, a Salvia officinalis diterpene, induces selective cytotoxicity in cancer cells. Cytotechnology. 2016;68(5):2139-2143. 2. Pratsinis H, et al. Antiproliferative activity of Greek propolis. J Med Food. 2010;13(2):286-290. 3. Nicolella HD, et al. Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells. Food Chem Toxicol. 2014;72:8-12. |
| 保存条件: |
-20℃ |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.443 ml |
17.213 ml |
34.426 ml |
| 5 mM |
0.689 ml |
3.443 ml |
6.885 ml |
| 10 mM |
0.344 ml |
1.721 ml |
3.443 ml |
| 50 mM |
0.069 ml |
0.344 ml |
0.689 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |