| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
V40108-1mg |
≥98% | ￥1050.00 |
货期：3-5天 | - | - | - | - |
|
V40108-5mg |
≥98% | ￥2640.00 |
货期：3-5天 | - | - | - | - |
|
V40108-10mg |
≥98% | ￥4040.00 |
货期：3-5天 | - | - | - | - |
|
V40108-25mg |
≥98% | ￥7260.00 |
货期：3-5天 | - | - | - | - |
|
V40108-50mg |
≥98% | ￥9790.00 |
货期：3-5天 | - | - | - | - |
|
V40108-100mg |
≥98% | ￥13200.00 |
货期：3-5天 | - | - | - | - |
|
| 体内研究： | The objectives of the present study are to characterize the metabolism, pharmacokinetics, and excretion of [14C] Gosogliptin in Sprague-Dawley (SD) rats, beagle dogs, and humans. A single dose of [14C] Gosogliptin is administered orally to intact SD rats (5 mg/kg), beagle dogs (5 mg/kg), and humans (20 mg). After a single oral dose of [14C] Gosogliptin to SD rats, an overall mean of 97.1% of the administered radioactivity is recovered in the urine, feces, and cage wash over a period of 168 h postdose. The mean cumulative dose recovered in feces is 66.0%. The mean cumulative excretion in the urine is 30.8%. Approximately 95% of the excreted radioactivity recovery occurred in the first 48 h. Mean total recoveries of dosed radioactivity from bile duct-cannulated rats are 29.5% in urine and 62.0% in bile. No gender-related differences are observed in the excretion pattern of radioactivity. | ||||||||||||||||||||
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| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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