货号	规格	价格	上海	北京	珠海	重庆	武汉
V43571-5mg	≥98%	￥170.00 V43571-5mg ￥170.00 3-5天	0 货期：3-5天	-	-	-	-
V43571-10mg	≥98%	￥280.00 V43571-10mg ￥280.00 3-5天	0 货期：3-5天	-	-	-	-
V43571-25mg	≥98%	￥560.00 V43571-25mg ￥560.00 3-5天	0 货期：3-5天	-	-	-	-
V43571-50mg	≥98%	￥910.00 V43571-50mg ￥910.00 3-5天	0 货期：3-5天	-	-	-	-
V43571-100mg	≥98%	￥1450.00 V43571-100mg ￥1450.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

Dodecanedioic acid-d4 is the deuterium labeled Dodecanedioic acid . Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus.

体外研究：

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

参考文献：

1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
2. Greco AV, et al. The metabolic effect of dodecanedioic acid infusion in non-insulin-dependent diabetic patien웿Ů

保存条件：

-20°C

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	4.267 ml	21.337 ml	42.675 ml
5 mM	0.853 ml	4.267 ml	8.535 ml
10 mM	0.427 ml	2.134 ml	4.267 ml
50 mM	0.085 ml	0.427 ml	0.853 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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