货号	规格	价格	上海	北京	珠海	重庆	武汉
V43626-1mg	≥98%	￥2000.00 V43626-1mg ￥2000.00 3-5天	0 货期：3-5天	-	-	-	-
V43626-5mg	≥98%	￥4800.00 V43626-5mg ￥4800.00 3-5天	0 货期：3-5天	-	-	-	-
V43626-10mg	≥98%	￥7670.00 V43626-10mg ￥7670.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

Spexin (Neuropeptide Q) is a selective agonist of galanin receptors GAL2 and GAL3, and is a conserved peptide that functions as a neurotransmitter/neuromodulator and endocrine factor. Spexin can function through both central and peripheral actions. Spexin upregulates Beclin 1 to inhibit ferroptosis induced by excessive autophagy, reduces the uptake of long-chain fatty acids by adipocytes, and regulates energy metabolism by increasing lipid oxidation (e.g., reducing the respiratory exchange ratio in rodents). Spexin improves cardiac function in the Doxorubicin hydrochloride -induced cardiotoxicity model, protects mitochondrial membrane potential, and reduces iron accumulation and lipid peroxidation. Spexin can be used to study obesity and its related metabolic disorders, cardiovascular diseases (e.g., cardioprotection), and side effects of tumor chemotherapy.

体外研究：

Spexin (1 μM；24 h) 增加 Doxorubicin 处理的新生大鼠心肌细胞 (NRCs) 活力并减少凋亡，逆转线粒体膜电位丢失并上调 GPX4/SLC7A11。
Spexin (20 ng/mL；2 h) 抑制分离的小鼠脂肪细胞长链脂肪酸 (LCFA) 摄取。

保存条件：

-20°C,干燥, 避光

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	0.617 ml	3.087 ml	6.173 ml
5 mM	0.123 ml	0.617 ml	1.235 ml
10 mM	0.062 ml	0.309 ml	0.617 ml
50 mM	0.012 ml	0.062 ml	0.123 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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