| 产品描述: | eIF4A3-IN-13 (compound 75) is a Silvestrol analogue. eIF4A3-IN-13 interferes the assembling of eIF4F translation complex with EC50s of 0.6, 15 and 0.4 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-13 can be used for the research of human cancer pathogenesis. |
| 参考文献: |
1. Liu T, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78.
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| 保存条件: |
2-8°C, 干燥, 避光 |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
1.961 ml |
9.804 ml |
19.609 ml |
| 5 mM |
0.392 ml |
1.961 ml |
3.922 ml |
| 10 mM |
0.196 ml |
0.98 ml |
1.961 ml |
| 50 mM |
0.039 ml |
0.196 ml |
0.392 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |