| 货号 | 规格 | 价格 | 上海 | 北京 | 珠海 | 重庆 | 武汉 | 购买数量 |
|---|---|---|---|---|---|---|---|---|
V43734-1mg |
≥98% | ￥530.00 |
货期：3-5天 | - | - | - | - |
|
V43734-5mg |
≥98% | ￥1190.00 |
货期：3-5天 | - | - | - | - |
|
V43734-10mg |
≥98% | ￥1990.00 |
货期：3-5天 | - | - | - | - |
|
V43734-25mg |
≥98% | ￥4490.00 |
货期：3-5天 | - | - | - | - |
|
V43734-50mg |
≥98% | ￥7180.00 |
货期：3-5天 | - | - | - | - |
|
| 产品描述： | GNE-9278 is a highly selective positive allosteric modulator of NMDAR that acts at the GluN1 transmembrane domain (TMD). GNE-9278 acts on activated NMDARs to increase peak current and agonist affinity. | ||||||||||||||||||||
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| 体外研究： | GNE-9278 (50 μM) slows deactivation with multiple agonists (D-Glu, L-Glu and L-CCG-IV) and enhances the potency of both Glu and Gly. GNE-9278 robustly potentiates GluN2A, 2B, 2C and 2D-containing NMDARs as measured by calcium influx assays from HEK cell lines with EC50s of 0.74, 3.07, 0.47, and 0.32 μM, respectively. |
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| 保存条件： | -20°C | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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