| 产品描述: | Anandamide-d8 is a deuterated labeled Anandamide. Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2). Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis. |
| 体外研究: |
氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱。 |
| 体内研究: |
Anandamide (10 mg/kg, IP, once) considerably lowers the increase of glycemia in response to glucose ingestion compared with control, and this is associated with an improvement of glucose tolerance. Anandamide (100 ng, ICV bilateral injection, single) p 웿 Ů ñ 샮㡽䇘睜⪰ޏࠃ 䇩睜 䇩睜Ȃ Ӥ 晐睦Ӥ 晐睦Ӥ 峀睜 弴睜 ڤ 犐ƈ ڤ郥댻嬧睜Ӥ 乨Ƥ鄩댻婯睜Љ �ޝ乜Ƥ媜睜 Ӥ ItemҮ쎾番莰ଁ뢜సങ獲䥷唍హ ⻌హ�唒⸼హ ଁ 敖ﰨ 唎Ӥ ﰰ 䨬{�唒⸼హ 쉢W⻌హ 稼Č 滛ﰰ靖 슸Wﰜ싛W幌Čﰰ䨬{ 싚W싢W幌Čﱈ䨔{犐ƈ >†靅댻EOF F It |
| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.812 ml |
14.062 ml |
28.123 ml |
| 5 mM |
0.562 ml |
2.812 ml |
5.625 ml |
| 10 mM |
0.281 ml |
1.406 ml |
2.812 ml |
| 50 mM |
0.056 ml |
0.281 ml |
0.562 ml |
|
| 注意: |
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