| 产品描述: | α-CGRP (mouse, rat), a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP (mouse, rat) can lead to a fall in blood pressure and an increase in heart rate by peripheral administration, also relax colonie smooth muscle. α-CGRP (mouse, rat) has the potential in cardiovascular, pro-inflammatory, migraine and metabolic studies. |
| 体外研究: |
α-CGRP (mouse, rat) 可调节 2 组先天淋巴样细胞反应。 α-CGRP (mouse, rat) 可调节胰岛素分泌,降低 2 型糖尿病的风险。 |
| 体内研究: |
α-CGRP (mouse, rat) (0.25, 0.5, 1 μg/kg/min, 静脉注射) 剂量依赖性地降低了平均动脉血压,同时心率和全身血管传导增加,而心输出量保持不变。 α-CGRP (mouse, rat) 在 Kainic acid (KA) 诱导的海马 CA3 区锥体细胞死亡的调控中发挥重要作用。 |
| 参考文献: |
1. Whitby K, et al. Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. J Virol. 2005 Jul;79(14):8698-706.
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| 保存条件: |
-80°C, 干燥 |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
0.263 ml |
1.314 ml |
2.627 ml |
| 5 mM |
0.053 ml |
0.263 ml |
0.525 ml |
| 10 mM |
0.026 ml |
0.131 ml |
0.263 ml |
| 50 mM |
0.005 ml |
0.026 ml |
0.053 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |