| 产品描述: | Alirinetide (GM604) is an oligopeptide containing 6 amino acids. Alirinetide can cross the blood-brain barrier and can be used for the research of multiple neurodegenerative diseases. |
| 体外研究: |
Alirinetide (GM604) (0.1-10 mg/mL; 24 h) prevents SH-SY5Y cell death. Alirinetide (48 h) predominantly represses Parkinson’s disease-associated genes in SH-SY5Y cells, these genes were largely associated with the mitochondrial protein complex and respiratory chain. |
| 参考文献: |
1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. |
| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.567 ml |
17.835 ml |
35.671 ml |
| 5 mM |
0.713 ml |
3.567 ml |
7.134 ml |
| 10 mM |
0.357 ml |
1.784 ml |
3.567 ml |
| 50 mM |
0.071 ml |
0.357 ml |
0.713 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |