货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
V44676-1mg	≥98%	￥570.00 V44676-1mg ￥570.00 3-5天	0 货期：3-5天	-	-	-	-
V44676-5mg	≥98%	￥1440.00 V44676-5mg ￥1440.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

ELND 006 (Compound 30) is a metabolically stable γ-secretase inhibitor designed to selectively inhibit amyloid beta (Aβ) generation while sparing Notch signaling. It was developed through a synthetic strategy emphasizing diversity and chirality. ELND 006, along with its analog ELND007 (Compound 34), progressed into human clinical trials. In preclinical studies, both compounds demonstrated effective reduction of Aβ levels in vitro and in vivo. Comparisons with other γ-secretase inhibitors like Semagacestat, Begacestat, and Avagacestat underscored their potency and specificity in lowering Aβ levels in cerebrospinal fluid (CSF) of healthy human volunteers, suggesting potential therapeutic efficacy in Alzheimer's disease.

保存条件：

-20°C, 干燥

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.196 ml	10.979 ml	21.959 ml
5 mM	0.439 ml	2.196 ml	4.392 ml
10 mM	0.22 ml	1.098 ml	2.196 ml
50 mM	0.044 ml	0.22 ml	0.439 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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