货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
V45049-1mg	≥98%	￥2790.00 V45049-1mg ￥2790.00 3-5天	0 货期：3-5天	-	-	-	-
V45049-5mg	≥98%	￥7500.00 V45049-5mg ￥7500.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

Kelatorphan is a full inhibitor of enkephalin degrading enzymes.

体外研究：

The administration of Kelatorphan alone (50 μg) could result in a strong increase of intact [3H]enkephalin content corresponding to 80±11% of total recovered radioactivity[2]. In normal awake rats, Kelatorphan (10±20 mg/kg i.v.) increases minute-volume. The increase in ventilation is due to a dose-dependent increase in breathing frequency. In arthritic rats Kelatorphan (20 mg/kg i.v.) increases ventilation and there is no significant difference between arthritic and non-arthritic rats. In pentobarbital-anesthetized rats, a slight (116%) but significant increase of respiration is also produced by Kelatorphan (20 mg/kg, n=6) 10±15 min after administration. The effects of Kelatorphan are not antagonized by a pretreatment with a small dose of naloxone (0.2 mg/kg i.v., 15 min before Kelatorphan), but a larger dose (1 mg/kg) significantly antagonized Kelatorphan (20 mg/kg) at 5 and 10 min in awake rats[3].

保存条件：

-20°C

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	3.398 ml	16.989 ml	33.979 ml
5 mM	0.68 ml	3.398 ml	6.796 ml
10 mM	0.34 ml	1.699 ml	3.398 ml
50 mM	0.068 ml	0.34 ml	0.68 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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