| 产品描述: | Scytonemin is a hydrophobic alkaloid pigment that can be isolated from the outer sheath of cyanobacteria. Scytonemin has protective function against short-wave solar ultraviolet (UV) radiation, which can reduce the generation of reactive oxygen species (ROS) and the formation of DNA damage. Scytonemin also has anti-inflammatory and anti-proliferative activities, produces concentration-dependent inhibition (IC50=2.0 μM) of polo-like kinase 1 (PLK1)-mediated cdc25C phosphorylation, and plays an important role in regulating the G2/M transition in the cell cycle. It can be used in the research of cancer, acute inflammation and sunscreen cosmetics. |
| 体外研究: |
Scytonemin (3 μM; 24 h) 抑制人 T 细胞白血病 Jurkat 细胞增殖 (IC50= 7.8 μM),并诱导细胞凋亡 (apoptosis)。 Scytonemin (100 nM-30 μM) 对 PDGF 诱导的 RSF 和 ECGF 诱导的 HUVEC 增殖具有抑制作用 (IC50=1.5 μM; IC50=5.4 μM) 。 |
| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
1.836 ml |
9.182 ml |
18.364 ml |
| 5 mM |
0.367 ml |
1.836 ml |
3.673 ml |
| 10 mM |
0.184 ml |
0.918 ml |
1.836 ml |
| 50 mM |
0.037 ml |
0.184 ml |
0.367 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |