货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
V45999-500μg	≥98%	￥2500.00 V45999-500μg ￥2500.00 3-5天	0 货期：3-5天	-	-	-	-
V45999-1mg	≥98%	￥4090.00 V45999-1mg ￥4090.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

Tranexamic acid-d2-1 is the deuterium labeled Tranexamic acid. Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

体外研究：

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

参考文献：

1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
2. Bhat A, et al. Tranexamic acid overdosage-induced generalized seizure in renal failure. Saudi J Kidney Dis Transpl. 2014 Jan-Feb;25(1):130-2.
3. Couturier R, et al. Continuous or discontinuous tranexamic acid effectively inhibits fibrinolysis in children undergoing cardiac surgery with cardiopulmonary bypass. Blood Coagul Fibrinolysis. 2014 Jan 13.

保存条件：

2-8°C, 干燥, 避光

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	6.281 ml	31.403 ml	62.806 ml
5 mM	1.256 ml	6.281 ml	12.561 ml
10 mM	0.628 ml	3.14 ml	6.281 ml
50 mM	0.126 ml	0.628 ml	1.256 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

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