| 产品描述: | Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research. |
| 体外研究: |
Promegestone (R-5020; 1 nM) is efficient ligand with a full agonist response profile and a low EC50 of 0.33 nM) in HELN-hPR while it only partially induced luciferase activity in U2OS-zfPR (EC50=1.93 nM). Promegestone is inactive in HELN cells that express luciferase but no functional receptor. Promegestone (10 nM) robustly stimulates SLC37A2 expression in cells expressing SUMO-deficient PR, but not in cells expressing WT PR in T47D cell models. |
| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.063 ml |
15.315 ml |
30.631 ml |
| 5 mM |
0.613 ml |
3.063 ml |
6.126 ml |
| 10 mM |
0.306 ml |
1.532 ml |
3.063 ml |
| 50 mM |
0.061 ml |
0.306 ml |
0.613 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |