货号	规格	价格	上海	北京	珠海	重庆	武汉
V46118-5mg	≥98%	￥660.00 V46118-5mg ￥660.00 3-5天	0 货期：3-5天	-	-	-	-
V46118-10mg	≥98%	￥1050.00 V46118-10mg ￥1050.00 3-5天	0 货期：3-5天	-	-	-	-
V46118-25mg	≥98%	￥2060.00 V46118-25mg ￥2060.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

TG8-260 is a second-generation EP2 antagonist developed to alleviate the pathology of central nervous system and peripheral diseases driven by inflammation. TG8-260 can reduce neuroinflammation and gliosis in the hippocampus of rats after pilocarpine-induced persistent epileptic status. Pharmacokinetic data of TG8-260 showed that its plasma half-life was 2.14 hours and its oral bioavailability was 77.3%. TG8-260 is also a potent inhibitor of CYP450 and shows antagonistic activity in inhibiting EP2 receptor-mediated inflammatory gene expression in BV2-hEP2 microglia, which is suitable for studying anti-inflammatory pathways in animal models of peripheral inflammatory diseases.

保存条件：

-20°C

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	2.904 ml	14.518 ml	29.035 ml
5 mM	0.581 ml	2.904 ml	5.807 ml
10 mM	0.29 ml	1.452 ml	2.904 ml
50 mM	0.058 ml	0.29 ml	0.581 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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