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SPR741

    
≥98%

源叶(MedMol)
V46205 一键复制产品信息
1179330-52-9
C44H73N13O13
992.13
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
V46205-1mg
≥98%

¥700.00

货期:3-5天 - - - -
V46205-5mg
≥98%

¥1500.00

货期:3-5天 - - - -
V46205-10mg
≥98%

¥2500.00

货期:3-5天 - - - -
V46205-25mg
≥98%

¥4500.00

货期:3-5天 - - - -
V46205-50mg
≥98%

¥7180.00

货期:3-5天 - - - -
V46205-100mg
≥98%

¥11400.00

货期:3-5天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: SPR741 (NAB741) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741.
体内研究: SPR741 has the ability to permeabilize the outer membrane of Gram-negative bacteria, thus sensitizing them to hydrophobic antibiotics. SPR741 has a significantly safety profile of compared to that of polymyxin B, which suffers severe, dose-limiting nephro￿웿￿￿Ů￿￿ñ샮㡽䇘睜⪰ޏࠃ䇩睜䇩睜ȂӤ晐睦Ӥ晐睦Ӥ峀睜弴睜
参考文献: 1. Corbett D, et al. Potentiation of Antibiotic Activity by a Novel Cationic Peptide: Potency and Spectrum of Activity of SPR741. Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00200-17.
2. Eckburg PB, et al. Safety, Tolerability, Pharmacokineti￿웿￿￿Ů￿￿ñ샮㡽䇘睜⪰ޏࠃ䇩睜䇩睜ȂӤ晐睦Ӥ晐睦Ӥ峀睜弴睜ڤ犐ƈڤ郥댻嬧睜Ӥ乨Ƥ鄩댻婯睜Љ�ޝ乜Ƥ媜睜ӤItemҮ
保存条件: -80°C, 干燥
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 1.008 ml 5.04 ml 10.079 ml
5 mM 0.202 ml 1.008 ml 2.016 ml
10 mM 0.101 ml 0.504 ml 1.008 ml
50 mM 0.02 ml 0.101 ml 0.202 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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