| 产品描述: | Microcolin H is a marine lipopeptide and phosphatidylinositol transfer protein ligand that targets PITPα/β. Microcolin H increases the conversion of LC3I to LC3II and reduces p62 levels in cancer cells, leading to autophagy cell death (Autophagy). Microcolin H effectively inhibits tumor development and has anti-proliferative activity in nude mouse subcutaneous tumor models. |
| 靶点: |
Phosphatidylinositol transfer protein, PITPα/β |
| 参考文献: |
1. Yang H et al. Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β. Signal Transduct Target Ther. 2023 Nov 15;8(1):428.
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| 保存条件: |
-20°C,干燥, 氮气保存 |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
1.363 ml |
6.813 ml |
13.625 ml |
| 5 mM |
0.273 ml |
1.363 ml |
2.725 ml |
| 10 mM |
0.136 ml |
0.681 ml |
1.363 ml |
| 50 mM |
0.027 ml |
0.136 ml |
0.273 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |