| 产品描述: | Ondansetron-d5 is the deuterium labeled Ondansetron . Ondansetron (GR 38032; SN 307) is a highly selective 5-HT3 receptor antagonist with an IC50 value of 103 pM. Ondansetron exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron can inhibit nausea and vomiting induced by chemotherapy and radiotherapy. |
| 体外研究: |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. |
| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
3.351 ml |
16.757 ml |
33.513 ml |
| 5 mM |
0.67 ml |
3.351 ml |
6.703 ml |
| 10 mM |
0.335 ml |
1.676 ml |
3.351 ml |
| 50 mM |
0.067 ml |
0.335 ml |
0.67 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |