货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
V46513-1mg	≥98%	￥2490.00 V46513-1mg ￥2490.00 3-5天	0 货期：3-5天	-	-	-	-

货号

规格

价格

上海

北京

珠海

重庆

武汉

购买数量

V46513-1mg

≥98%

￥2490.00

货期：3-5天

产品描述：

Ethambutol-d10 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.

体外研究：

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

参考文献：

1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
2. Ethambutol. Tuberculosis (Edinb), 2008. 88(2): p. 102-5.
3. Rastogi, N., V. Labrousse, and K.S. Goh, In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages. Curr Microbiol, 1996. 33(3): p. 167-75.
4. Kaur, D. and G.K. Khuller, In vitro, ex-vivo and in vivo activities of ethambutol and sparfloxacin alone and in combination against mycobacteria. Int J Antimicrob Agents, 2001. 17(1): p. 51-5.

保存条件：

-20°C

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	4.665 ml	23.324 ml	46.648 ml
5 mM	0.933 ml	4.665 ml	9.33 ml
10 mM	0.466 ml	2.332 ml	4.665 ml
50 mM	0.093 ml	0.466 ml	0.933 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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