货号	规格	价格	上海	北京	珠海	重庆	武汉
V46821-1mg	≥98%	￥870.00 V46821-1mg ￥870.00 3-5天	0 货期：3-5天	-	-	-	-
V46821-5mg	≥98%	￥2190.00 V46821-5mg ￥2190.00 3-5天	0 货期：3-5天	-	-	-	-
V46821-10mg	≥98%	￥3290.00 V46821-10mg ￥3290.00 3-5天	0 货期：3-5天	-	-	-	-
V46821-25mg	≥98%	￥5590.00 V46821-25mg ￥5590.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

MMI-0100 is a cell-permeant peptide inhibitor of mitogen activated protein kinase activated protein kinase II (MK2). MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. MMI-0100 suppresses IL-6 expression without effect on IL-8 expression. MMI-0100 suppresses fibrotic processes such as vein graft disease.

体外研究：

Naphthofluorescein (compound 19) (0-10 μM; 24 hours) suppresses the HIF-1 reporter activity in a concentration-dependent manner. .
MMI-0100 (0.25 and 0.5 mM; 24 hours) slightly increases cell proliferation in both cell types compared to control cells treated with 20 ng/ml TNF-α alone.
MMI-0100 (1 mM) treatment also increases both EC (11%) and SMC (7%) proliferation as compared to control, this response is not as robust as that induced by treatment with 0.5 mM MMI-0100.
MMI-0100 does not induce EC apoptosis at any dose.

保存条件：

-20°C, 干燥, 避光, 氮气保存

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	0.438 ml	2.189 ml	4.379 ml
5 mM	0.088 ml	0.438 ml	0.876 ml
10 mM	0.044 ml	0.219 ml	0.438 ml
50 mM	0.009 ml	0.044 ml	0.088 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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