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Avacincaptad pegol sodium

    
≥98%

源叶(MedMol)
V47211 一键复制产品信息
1491144-00-3
53500 (Approximately)
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
V47211-1mg
≥98%

¥3680.00

货期:3-5天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: Avacincaptad pegol (ARC1905) sodium is a 40KDa PEG-conjugated aptamer. Avacincaptad pegol sodium targets complement factor 5 (C5), inhibits the cleavage of C5 into C5a and C5b, limits inflammatory stimulation and complement membrane attack complex (MAC), and is used to study age-related macular degeneration (AMD). Avacincaptad pegol sodium limits irregular cell apoptosis by targeting downstream factors in the complement cascade while preserving the early steps of the complement system. Avacincaptad pegol sodium treats Geographic atrophy (GA) mice.
参考文献: 1. Joshua Ong, et al. The Complement System as a Therapeutic Target in Retinal Disease. Medicina (Kaunas). 2024 Jun 5;60(6):945.
2. Yiming Li, et al. Targeting both C5 and HTRA1 provides additional rescue effect in NaIO3-induce GA model. IOVS. June 202￿웿￿￿Ů￿￿ñ샮㡽䇘睜⪰ޏࠃ䇩睜䇩睜ȂӤ晐睦Ӥ晐睦Ӥ峀睜弴睜ڤ犐ƈڤ郥댻嬧睜Ӥ乨Ƥ鄩댻婯睜Љ�ޝ乜Ƥ媜睜ӤItemҮ쎾番莰ଁ뢜సങ獲䥷唍⋠హ⾈హ�唒⻸హଁ敖ﰨ唎֞ﰰ䨬{�唒⻸హ쉢W⾈హ稼Č滛ﰰ靖슸W﫨ﰜ싛W﫨幌Čﰰ䨬{ 싚W싢W幌Čﱈ䨔{犐ƈ>†靅댻EOFFItemCount婯睜Љɾ쎾番荘ଁ랜సiﰜﶴﱌ랜సﱬ먙唌랜స荘ଁiﰜﶴﱌ먰唌荘ଁ 翨Ƅ杹畦茀ଁ莰ଁ翨
保存条件: -20°C, 干燥
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 0 ml 0 ml 0 ml
5 mM 0 ml 0 ml 0 ml
10 mM 0 ml 0 ml 0 ml
50 mM 0 ml 0 ml 0 ml
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参考文献

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摩尔浓度计算器

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