| 产品描述: | HAEGTFTSD is a 9-residue peptide of human GLP-1 peptide or GLP-1(7-36), amide . GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretionin a glucose-dependant manner |
| 体外研究: |
The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists. |
| 体内研究: |
Pyk2-IN-2 (compound 13j) 的 HLM 血液清除率 为 31 mL/min/kg。 |
| 保存条件: |
-20°C,干燥, 避光 |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
1.037 ml |
5.187 ml |
10.374 ml |
| 5 mM |
0.207 ml |
1.037 ml |
2.075 ml |
| 10 mM |
0.104 ml |
0.519 ml |
1.037 ml |
| 50 mM |
0.021 ml |
0.104 ml |
0.207 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |