货号	规格	价格	上海	北京	珠海	重庆	武汉
V47752-1mg	≥98%	￥450.00 V47752-1mg ￥450.00 3-5天	0 货期：3-5天	-	-	-	-
V47752-5mg	≥98%	￥1120.00 V47752-5mg ￥1120.00 3-5天	0 货期：3-5天	-	-	-	-
V47752-10mg	≥98%	￥1800.00 V47752-10mg ￥1800.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA).

体外研究：

Peptide 78, a potent PMN chemotaxin, in the conditioned medium of human pulmonary epithelial cells (A549) stimulated with TNF-α (20 ng/mL) or IL-1β (10 ng/mL). Peptide 78 is an 8.3-kD protein with 78 amino acids containing 4 cysteines positioned identically to those of IL-8 and its homologues. Peptide 78 belongs to a supergene family that includes platelet factor-4, platelet basic protein, and its cleavage products (connective tissue activating peptide-III, β-thromboglobulin, and interferon-γ-inducible protein, macrophage inflammatory protein-2α, and macrophage inflammatory protein-2β).
Peptide 78 shares several properties of PMN activation similar to either NAP-2 or LL-8. Peptide 78 stimulation of PMNs results in significant chemotactic activity, release of elastase from cytochalasin-B-pretreated cells, and the induction of free, cytosolic calcium release. Peptide 78 aids in the recruitment of PMNs into inflamed joints of RA. Peptide 78 represents one of the most abundant chemokines present in RA synovial fluid.Peptide 78 in rheumatoid arthritis synovial fluids is biologically active. Peptide 78 appears to account for almost half of the RA synovial fluid PMN chemotactic activity in vitro.

保存条件：

-20°C, 干燥

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	0.648 ml	3.241 ml	6.482 ml
5 mM	0.13 ml	0.648 ml	1.296 ml
10 mM	0.065 ml	0.324 ml	0.648 ml
50 mM	0.013 ml	0.065 ml	0.13 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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