| 产品描述: | PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA. |
| 参考文献: |
1. Hobo W, , et al. Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation. Cancer Immunol Immunother. 2013 Feb;62(2):285-97. |
| 保存条件: |
-20°C, 氮气保存 |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
0.383 ml |
1.915 ml |
3.831 ml |
| 5 mM |
0.077 ml |
0.383 ml |
0.766 ml |
| 10 mM |
0.038 ml |
0.192 ml |
0.383 ml |
| 50 mM |
0.008 ml |
0.038 ml |
0.077 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |