货号	规格	价格	上海	北京	珠海	重庆	武汉
V48307-5mg	≥98%	￥2790.00 V48307-5mg ￥2790.00 3-5天	0 货期：3-5天	-	-	-	-
V48307-10mg	≥98%	￥4490.00 V48307-10mg ￥4490.00 3-5天	0 货期：3-5天	-	-	-	-
V48307-25mg	≥98%	￥8080.00 V48307-25mg ￥8080.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

NSD-IN-3 (compound 3) is a potent nuclear receptor binding SET domain (NSD) inhibitor. NSD-IN-3 inhibits NSD2-SET and NSD3-SET with IC50 values of 0.81 μM and 0.84 μM, respectively. NSD-IN-3 inhibits histone H3K36 dimethylation and decreases the expression of NSDs-targeted genes in non-small cell lung cancer cells. NSD-IN-3 induces s-phase cell cycle arrest and apoptosis.

体外研究：

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
1. 4-Di-10-ASP (1 μM), DOPC (10 mM), and DOPG.html" class="link-product" target="_blank">DOPG (1 mM) is dissolved in methanol/chloroform (25 L, 1:2 v/v).
2. The solution is allowed to dry overnight under vacuum to obtain lamellar lipid films, which in turn are hydrated with the transcription/translation solution (25 L) for three hours at 37℃.
3. An aliquot (10 L) of the solution thus prepared is placed on a glass slide and sealed by a cover glass.
4. The sample is immediately observed with a confocal laser-scanning microscope, an argon laser (488 nm) is employed to excite the 4-Di-10-ASP.

保存条件：

2-8°C, 干燥, 避光

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	1.616 ml	8.081 ml	16.162 ml
5 mM	0.323 ml	1.616 ml	3.232 ml
10 mM	0.162 ml	0.808 ml	1.616 ml
50 mM	0.032 ml	0.162 ml	0.323 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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