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H1PVAT

    
≥90%

源叶(MedMol)
V48647 一键复制产品信息
351438-49-8
C19H14F3N5OS
417.41
货号 规格 价格 上海 北京 珠海 重庆 武汉 购买数量
V48647-5mg
≥90%

¥1190.00

货期:3-5天 - - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品
产品描述: H1PVAT is a potent and selective inhibitor of poliovirus serotypes (PV-1, PV-2, PV-3), and inhibits early stage of the replication. H1PVAT interacts with viral capsid directly and protects PV against heat inactivation.
体外研究: H1PVAT (10-218 nM; 24-48 h) inhibits poliovirus strain Sabin replication in a dose-dependent manner, with EC50s of 10 nM (PV-1), 26 nM (PV-2) and 218 nM (PV-3), respectively.

H1PVAT (30 min prior to or 1 h after PV-1 infection; 7 h) inhibits an early stage of viral replication , and only H1PVAT is administered prior to infection results reduction (>99.9%) in intracellular viral RNA levels.

H1PVAT (50 μM; 2 min) protects PV against heat inactivation with the 50% thermal inactivation temperature increased to 52.6 ℃ and 50.8 ℃, which suggests a direct interaction between the viral capsid and H1PVAT.
保存条件: -20°C
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.396 ml 11.979 ml 23.957 ml
5 mM 0.479 ml 2.396 ml 4.791 ml
10 mM 0.24 ml 1.198 ml 2.396 ml
50 mM 0.048 ml 0.24 ml 0.479 ml
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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