货号	规格	价格	上海	北京	珠海	重庆	武汉
V48702-1mg	≥90%	￥400.00 V48702-1mg ￥400.00 3-5天	0 货期：3-5天	-	-	-	-
V48702-5mg	≥90%	￥1000.00 V48702-5mg ￥1000.00 3-5天	0 货期：3-5天	-	-	-	-
V48702-10mg	≥90%	￥1600.00 V48702-10mg ￥1600.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

IT9302 is a synthetic IL-10 agonist with the activity of inducing tolerogenic dendritic cells. IT9302 is able to mimic multiple effects of IL-10, including downregulating the antigen presentation machinery and increasing the sensitivity of tumor cells to natural killer cell-mediated lysis. IT9302 can also hinder the response of human monocytes to differentiation factors and reduce the antigen presentation and co-stimulatory capacity of dendritic cells. Dendritic cells treated with IT9302 showed a weakened ability to stimulate T cell proliferation and interferon-γ production. IT9302 exerts its effects through mechanisms that are partially different from IL-10, involving STAT3 inactivation and regulation of the NF-κB intracellular pathway. IT9302-treated dendritic cells showed enhanced expression of membrane-bound TGF-β, associated with the effective induction of foxp3+ regulatory T cells.

保存条件：

-20°C, 干燥

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	0.887 ml	4.435 ml	8.87 ml
5 mM	0.177 ml	0.887 ml	1.774 ml
10 mM	0.089 ml	0.444 ml	0.887 ml
50 mM	0.018 ml	0.089 ml	0.177 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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摩尔浓度计算器

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