| 产品描述: | Fosmanogepix (APX001) is a broad-spectrum agent against invasive fungal infections. Fosmanogepix (APX001) targets the conserved Gwt1 enzyme required for the localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. This inhibition prevents the appropriate localization of cell wall mannoproteins, which compromises cell wall integrity, biofilm formation, germ tube formation, and fungal growth. Fosmanogepix (APX001) can be used for invasive fungal infections research. |
| 体外研究: |
Fosmanogepix (APX001) (2-0.002 μg/ml, 40-72小时) 抑制新生梭菌、加蒂梭菌、白色念珠菌和烟曲霉生长的最低有效浓度为 0.008-0.25 μg/ml。 |
| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.135 ml |
10.675 ml |
21.349 ml |
| 5 mM |
0.427 ml |
2.135 ml |
4.27 ml |
| 10 mM |
0.213 ml |
1.067 ml |
2.135 ml |
| 50 mM |
0.043 ml |
0.213 ml |
0.427 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |