货号	规格	价格	上海	北京	珠海	重庆	武汉	购买数量
V49128-1mg	≥98%	￥2160.00 V49128-1mg ￥2160.00 3-5天	0 货期：3-5天	-	-	-	-
V49128-5mg	≥98%	￥5400.00 V49128-5mg ￥5400.00 3-5天	0 货期：3-5天	-	-	-	-

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产品描述：

L-Theanine-d5 is the deuterium labeled L-Theanine. L-Theanine (L-Glutamic Acid γ-ethyl amide）is a non-protein amino acid contained in green tea leaves, which blocks the binding of L-glutamic acid to glutamate receptors in the brain, and with neuroprotective and anti-oxidative activities. L-Theanine causes anti-stress effects via the inhibition of cortical neuron excitation by oral intake.

体外研究：

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

参考文献：

1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
2. Vuong QV, et al. L-Theanine: properties, synthesis and isolation from tea. J Sci Food Agric. 2011 Aug 30;91(11):1931-9.
3. Kimura K, et al. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007 Jan;74(1):39-45.
4. Takeshima M, et al. l-Theanine protects against excess dopamine-induced neurotoxicity in the presence of astrocytes. J Clin Biochem Nutr. 2016 Sep;59(2):93-99.

保存条件：

-20°C, 氮气保存

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	5.579 ml	27.897 ml	55.794 ml
5 mM	1.116 ml	5.579 ml	11.159 ml
10 mM	0.558 ml	2.79 ml	5.579 ml
50 mM	0.112 ml	0.558 ml	1.116 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献

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