| 产品描述: | Maleic hydrazide-d2 is the deuterium labeled Maleic hydrazide. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins. |
| 体外研究: |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. |
| 参考文献: |
1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. 2. Venezian A, et al. The Influence of the Plant Growth Regulator Maleic Hydrazide on Egyptian Broomrape Early Developmental Stages and Its Control Efficacy in Tomato under Greenhouse and Field Conditions. Front Plant Sci. 2017;8:691. Published 2017 May 16. 3. Swietlińska Z, et al. Cytotoxic effects of maleic hydrazide. Mutat Res. 197855(1):15-30. 4. Yurdakok B, et al. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells. Drug Chem Toxicol. 201437(4):459-465. |
| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
8.764 ml |
43.821 ml |
87.642 ml |
| 5 mM |
1.753 ml |
8.764 ml |
17.528 ml |
| 10 mM |
0.876 ml |
4.382 ml |
8.764 ml |
| 50 mM |
0.175 ml |
0.876 ml |
1.753 ml |
|
| 注意: |
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