| 产品描述: | IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage. |
| 参考文献: |
1. Faid V, et al., Middle-up analysis of monoclonal antibodies after combined IgdE and IdeS hinge proteolysis: Investigation of free sulfhydryls. J Pharm Biomed Anal. 2018 Feb 5;149:541-546.
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| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
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| 50 mM |
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| 注意: |
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