| 产品描述: | Diethyl succinate-13C4 is the 13C labeled Diethyl succinate. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring. |
| 体外研究: |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. |
| 参考文献: |
1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. 2. Zacharias NM, et al. Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolar 웿 Ů ñ 샮㡽䇘睜⪰ޏࠃ |
| 保存条件: |
-20°C |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
5.613 ml |
28.065 ml |
56.129 ml |
| 5 mM |
1.123 ml |
5.613 ml |
11.226 ml |
| 10 mM |
0.561 ml |
2.806 ml |
5.613 ml |
| 50 mM |
0.112 ml |
0.561 ml |
1.123 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |