| 产品描述: | 易溶于碱性水溶液,其颜色随pH不同而变化,微溶于水(0·2 g/L)、不溶于乙醚、乙醇和其他非极性有机溶剂。在pH>5时微溶于水。pH<5时溶解度降低。 |
| 体内研究: |
Alizarin complexone (3.13-200 mg/kg;皮下注射;连续 6 天) 可延缓 RSV 在3日龄 SPAFAS 鸡中的肿瘤诱导,将平均生存时间从 14.0 天延长至 18.5 天。 Alizarin complexone (0.75 mg/mL,10 μL;关节内注射) 可检测到 11-12 周龄雄性 C57BL/6J 小鼠 (患有 DMM 诱发的早期骨关节炎) 从关节软骨到软骨下骨的通透性增加以及骨膜渗透性增强。 |
| 参考文献: |
1. Higuchi H, et al. Antiretroviral activities of anthraquinones and their inhibitory effects on reverse transcriptase. Antiviral Res. 1991;15(3):205-216. 2. Oshima T, et al. Selective extraction of histidine derivatives by metal affinity with a copper(II)-chelating ligand complex in an aqueous two-phase system. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;990:73-79. 3. Yu T, et al. Live imaging of osteoclast inhibition by bisphosphonates in a medaka osteoporosis model. Dis Model Mech. 2016 Feb;9(2):155-63. 4. Cui M, et al. New role of calcium-binding fluorescent dye alizarin complexone in detecting permeability from articular cartilage to subchondral bone. FASEB Bioadv. 2024 Oct 7;6(11):539-554. |
| 保存条件: |
-80℃(运输条件:冰袋低温运输) |
| 配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
| 1 mM |
2.595 ml |
12.976 ml |
25.952 ml |
| 5 mM |
0.519 ml |
2.595 ml |
5.19 ml |
| 10 mM |
0.26 ml |
1.298 ml |
2.595 ml |
| 50 mM |
0.052 ml |
0.26 ml |
0.519 ml |
|
| 注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |